Using the nontoxic heavy chain fragment from botulinum neurotoxins A-G, compositions and methods of use in inducing an immune response which is protective against intoxication with botulinum in subjects is described.
申请公布号
EP1119626(B1)
申请公布日期
2008.01.02
申请号
EP19990940801
申请日期
1999.07.09
申请人
U.S. ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES
发明人
LEE, JOHN, S.;PUSHKO, PETER;SMITH, JONATHAN, F.;PARKER, MICHAEL;DERTZBAUGH, MARK, T.;SMITH, LEONARD