摘要 |
It has been found that the nitration of pyridine-2,6-diamines, which is commonly performed in a mixture of nitric acid and concentrated sulphuric acid, will give a significantly higher yield (from about 50 % up t o more than 90 %) if the reaction is carried out in a mixture of nitric acid and oleum, or by otherwise providing an inherently anhydrous medium.
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