| 摘要 |
PROBLEM TO BE SOLVED: To provide tablets keeping imidapril hydrochloride stable therein for a long period. SOLUTION: The tablets are each composed of imidapril hydrochloride and ingredients in terms of pharmaceutical preparation, wherein a lubricant as one of the ingredients contains no metal ion. Among the ingredients, as the lubricant, a hydrogenated oil, glycerol fatty acid ester, sucrose fatty acid ester, carnauba wax or white beeswax, as an excipient, lactose, D-mannitol, erythritol or trehalose, as a binder, polyvinyl alcohol(partially saponified product thereof), methyl cellulose or pullulan, and as an disintegrant, carmellose, can be preferably used. COPYRIGHT: (C)2008,JPO&INPIT
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