发明名称 |
Gag antigen and its use for the detection of lav infection and in immunogenic compositions |
摘要 |
Purified material (I) contg. the polypeptide back bone of a glycoprotein of molecular wt. about 110,000, or antigen of lower molecular wt. derived from it, is new. (I) is recognised by sera of human origin and contg. antibodies against the virus of lymphadenopathies (LAV) or acquired immune deficiency syndrome (AIDS). Peptides corresp. to the aminoacid sequences deducible from proteins encoded by LAV DNA are new, when defined by specific residues, e.g. 12-32, 37-46, 49-79, 88-153 etc. |
申请公布号 |
EP1279678(B1) |
申请公布日期 |
2007.09.12 |
申请号 |
EP20020017001 |
申请日期 |
1985.10.18 |
申请人 |
INSTITUT PASTEUR;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
MONTAGNIER, LUC;KRUST, BERNARD;CHAMARET, SOLANGE;CLAVEL, FRANCOIS;CHERMANN, JEAN-CLAUDE;BARRE-SINOUSSI, FRANCOISE;ALIZON, MARC;SONIGO, PIERRE;STEWART, COLE;DANOS, OLIVIER;WAIN-HOBSON, SIMON |
分类号 |
C07K14/16;G01N33/53;A61K38/00;A61K39/00;A61K39/21;A61P31/12;A61P31/18;C07H21/04;C07K1/00;C07K7/06;C07K7/08;C07K14/15;C07K14/155;C07K14/705;C07K16/00;C07K16/10;C12N15/09;C12N15/49;C12P21/00;C12P21/02;C12P21/08;C12Q1/70;C12R1/91;G01N33/531;G01N33/569;G01N33/577 |
主分类号 |
C07K14/16 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|