| 摘要 |
<p>The present invention is directed to methods of transfecting cells with siRNA, by contacting a transfection complex with one or more cells, where the transfection complex includes a transport polymer and siRNA. The transport polymer may include for example, H3K8b and/or structurally similar compounds. The invention is also directed to such transfection complexes, and to compositions that include such transfection complexes. The invention is further directed to methods of treating patients using the transfection complexes of the present invention. Polymer Structure of Branched Polymers Sequence of Domains H3K8b H8=HHHHNHHHH R=HHHKHHHKHHHK- HHH H3K4b R=KHHHKHHHKHHH- KHHHK H2K4b R=KHKHHKHHKHH- KHHKHHKHK HK4b R=KHKHKHKHKHKH- KHKHKHK</p> |
