发明名称 Branched carboxylic acid compound and use thereof
摘要 The present invention relates to a compound represented by formula (I) wherein R<SUP>1 </SUP>represents optionally protected hydroxy or oxo, <img id="custom-character-00001" he="3.13mm" wi="7.79mm" file="US20070167522A1-20070719-P00001.TIF" alt="custom character" img-content="character" img-format="tif"/> indicates alpha-configuration, beta-configuration or a mixture of these in an arbitary proportion, n represents an integer of 1 to 3, and m represents 0 or an integer of 1 to 10; and wherein two or more R<SUP>1</SUP>'s are not bound to the same carbon atom other than the terminal carbon atom, a salt thereof or a prodrug thereof. The compounds represented by formula (I) have an ability to improve astrocyte function, and they are useful as a preventive and/or therapeutic agent for a brain infarction, neuronal dysfunction by brain infarction, Parkinson's disease, Parkinson's syndrome, amyotrophic lateral sclerosis or Alzheimer's disease.
申请公布号 US2007167522(A1) 申请公布日期 2007.07.19
申请号 US20040564720 申请日期 2004.07.14
申请人 ONO PHARMACEUTICAL CO LTD 发明人 IMAWAKA HARUO;HASEGAWA TOMOYUKI;SAKUYAMA SHIGERU;KAWANAKA YASUFUMI;AKIYAMA TSUTOMU;HOSHIKAWA MASAMITSU;MATSUDA SAIKO
分类号 A61K31/20;A61P25/00;A61P25/14;A61P25/16;A61P25/28;C07C59/01;C07C59/185 主分类号 A61K31/20
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