发明名称 |
Whole cell assay involving cathepsin s |
摘要 |
The present invention relates to a method of identifying and evaluating chemical inhibitors of cathepsin S activity in whole cells. The present invention also relates to probes that are capable of forming irreversible adducts with cathepsin S at the active site. The probes used in the instant invention comprise radioactive functional groups to allow the detection of the irreversible cathepsin S-probe adducts.
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申请公布号 |
US2007026477(A1) |
申请公布日期 |
2007.02.01 |
申请号 |
US20060571016 |
申请日期 |
2006.03.03 |
申请人 |
FALGUEYRET JEAN-PIERRE;MELLON CHRISTOPHE |
发明人 |
FALGUEYRET JEAN-PIERRE;MELLON CHRISTOPHE |
分类号 |
C12Q1/48;C07C245/02;C07C245/14;C12Q1/37;G01N33/50 |
主分类号 |
C12Q1/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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