发明名称 |
Use of tempol for the treatment of Li-Fraumeni syndrome and ataxia telangiectasia |
摘要 |
The present invention provides a method for the prophylactic and therapeutic treatment of cancer. The method comprises administering to an animal, preferably a mammal, more preferably a human, at risk for developing a cancer or having a cancer a nitroxide or a prodrug thereof, wherein the nitroxide or prodrug thereof preferably is alicyclic or heterocyclic and more preferably is a compound of Formula (I) or Formula (II): in an amount sufficient to prevent or treat said cancer, wherein said cancer is susceptible to prevention or treatment by said nitroxide or prodrug thereof. Also provided is a composition for use in the method
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申请公布号 |
US7153866(B1) |
申请公布日期 |
2006.12.26 |
申请号 |
US20000424519 |
申请日期 |
2000.03.03 |
申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
MITCHELL JAMES B.;RUSSO ANGELO;CHERUKURI MURALI KRISHNA;DELUCA ANNE MARIE |
分类号 |
A61K31/445;A61K31/42;A61K31/44 |
主分类号 |
A61K31/445 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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