发明名称 |
Method for in vitro detection aberrant dysplasia, and the artificial nucleotides being used |
摘要 |
The present invention provides a method for in vitro detection of malignant potential of dysplasia by aberrant methylation of p16 CpG islands, comprising extraction of genomic DNA from a tissue or body fluid sample, analysis of methylation status of p16 CpG islands in the extracted DNA, and evaluation of malignant potential of the tested tissue. The present invention also provides DNA compositions having artificial sequences of p16 CpG islands with or without methylation.
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申请公布号 |
US2006252043(A1) |
申请公布日期 |
2006.11.09 |
申请号 |
US20050549252 |
申请日期 |
2005.12.05 |
申请人 |
BAI HUA;SUN YU;ZHOU JING;LI JIYOU;DENG DAJUN |
发明人 |
BAI HUA;SUN YU;ZHOU JING;LI JIYOU;DENG DAJUN |
分类号 |
C12Q1/68;C07H21/04 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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