| 发明名称 |
PROCESS FOR PREPARING CRYSTALLINE FORM I OF CABERGOLINE |
| 摘要 |
A process for producing crystalline form I of cabergoline, which process comprises the preparation of Form V using heptane as precipitation solvent, and its exclusive conversion into crystalline Form I of cabergoline. The present crystallization process from toluene-heptane solvent system for form V involves "reverse addition" of toluene-cabergoline concentrate to cold heptane.
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| 申请公布号 |
RS81804(A) |
申请公布日期 |
2006.10.27 |
| 申请号 |
YU2004P000818 |
申请日期 |
2003.03.10 |
| 申请人 |
PHARMACIA CORPORATION;PHARMACIA ITALIA S.P.A. |
发明人 |
SHEIKH AHMAD;TOMASI ATTILIO |
| 分类号 |
C07D471/04;A61K31/42;A61K31/437;A61P25/00;A61P25/16;C07D261/08;C07D457/06;(IPC1-7):C07D457/06 |
主分类号 |
C07D471/04 |
| 代理机构 |
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代理人 |
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