发明名称 |
Sulfonyl aryl or heteroaryl hydroxamic acid compounds |
摘要 |
A sulfonyl aromatic or heteroaromatic ring hydroxamic acid compound that inter alia inhibits matrix metalloprotease activity is disclosed as are a treatment process that comprises administering a contemplated sulfonyl aromatic or heteroaromatic ring hydroxamic acid compound in a MMP enzyme-inhibiting effective amount to a host having a condition associated with pathological matrix metalloprotease activity. A contemplated compound corresponds in structure to the formula wherein W and the R groups are defined elsewhere.
|
申请公布号 |
US7115632(B1) |
申请公布日期 |
2006.10.03 |
申请号 |
US20000569034 |
申请日期 |
2000.05.11 |
申请人 |
G. D. SEARLE & CO. |
发明人 |
BEDELL LOUIS J;MCDONALD JOSEPH J;BARTA THOMAS E;BECKER DANIEL P;SHASHIDHAR RAO N;FRESKOS JOHN N;MISCHKE BRENT V;GETMAN DANIEL P;DECRESCENZO GARY A;VILLAMIL CLARA I |
分类号 |
A61K31/445;C07C311/16;C07C311/21;C07C317/44;C07D207/48;C07D211/96;C07D295/26;C07D401/12 |
主分类号 |
A61K31/445 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|