发明名称 Sulfonyl aryl or heteroaryl hydroxamic acid compounds
摘要 A sulfonyl aromatic or heteroaromatic ring hydroxamic acid compound that inter alia inhibits matrix metalloprotease activity is disclosed as are a treatment process that comprises administering a contemplated sulfonyl aromatic or heteroaromatic ring hydroxamic acid compound in a MMP enzyme-inhibiting effective amount to a host having a condition associated with pathological matrix metalloprotease activity. A contemplated compound corresponds in structure to the formula wherein W and the R groups are defined elsewhere.
申请公布号 US7115632(B1) 申请公布日期 2006.10.03
申请号 US20000569034 申请日期 2000.05.11
申请人 G. D. SEARLE & CO. 发明人 BEDELL LOUIS J;MCDONALD JOSEPH J;BARTA THOMAS E;BECKER DANIEL P;SHASHIDHAR RAO N;FRESKOS JOHN N;MISCHKE BRENT V;GETMAN DANIEL P;DECRESCENZO GARY A;VILLAMIL CLARA I
分类号 A61K31/445;C07C311/16;C07C311/21;C07C317/44;C07D207/48;C07D211/96;C07D295/26;C07D401/12 主分类号 A61K31/445
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