发明名称 BIOACTIVE FUS1 PEPTIDES AND NANOPARTICLE-POLYPEPTIDE COMPLEXES
摘要 A nanoparticle-polypeptide complex comprising a bioactive polypeptide in association with a nanoparticle, wherein the bioactive polypeptide is modified by the addition of a chemical moiety that facilitates cellular uptake of the protein. The polypeptide can be a protein or a peptide. In some embodiments, the amino acid sequence of the protein or peptide is derived from the amino acid sequence of a tumor suppressor gene product.
申请公布号 CA2600370(A1) 申请公布日期 2006.09.14
申请号 CA20062600370 申请日期 2006.03.14
申请人 BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 发明人 LIN, JACKI;OZPOLAT, BULENT;LOPEZ-BERESTEIN, GABRIEL;ROTH, JACK A.;JI, LIN X.;SUN, TONG;ARLINGHAUS, RALPH B.
分类号 C07K14/47;A61K9/127;A61K31/506;A61K38/10;A61K38/16;A61K47/12;A61K47/14;A61K47/48;A61P35/00;C07K7/08;C12N9/12 主分类号 C07K14/47
代理机构 代理人
主权项
地址