BIOACTIVE FUS1 PEPTIDES AND NANOPARTICLE-POLYPEPTIDE COMPLEXES
摘要
A nanoparticle-polypeptide complex comprising a bioactive polypeptide in association with a nanoparticle, wherein the bioactive polypeptide is modified by the addition of a chemical moiety that facilitates cellular uptake of the protein. The polypeptide can be a protein or a peptide. In some embodiments, the amino acid sequence of the protein or peptide is derived from the amino acid sequence of a tumor suppressor gene product.
申请公布号
CA2600370(A1)
申请公布日期
2006.09.14
申请号
CA20062600370
申请日期
2006.03.14
申请人
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
发明人
LIN, JACKI;OZPOLAT, BULENT;LOPEZ-BERESTEIN, GABRIEL;ROTH, JACK A.;JI, LIN X.;SUN, TONG;ARLINGHAUS, RALPH B.