COMPOSITIONS AND METHODS FOR DETECTING PATHOGEN SPECIFIC NUCLEIC ACIDS IN URINE
摘要
The invention is based upon the discovery that small nucleic acids from non- viral pathogens are able to cross the kidney and are present in urine of a subject when the subject is infected with the non- viral pathogen. These transrenal DNAs are especially prevalent at smaller sizes under about 300 bp. Thus the invention provides compositions and methods for the diagnosis of infection of a subject with non- viral pathogens through the detection of transrenal nucleic acids from those pathogens in the urine of the subject.
申请公布号
CA2609636(A1)
申请公布日期
2006.08.24
申请号
CA20062609636
申请日期
2006.02.14
申请人
ISTITUTO NAZIONALE PER LE MALATTIE INFETTIVE IRCCS LAZZARO SPALLANZANI
发明人
CANNAS, ANGELA;TOMEI, LOUIS DAVID;UMANSKY, SAMUIL R.;MILKMAN, HOOVES