发明名称 IMMUNOGLOBULINS WHITH POTENT AND BROAD ANTIVIRAL ACTIVITY
摘要 <p>A. (poly)peptide-Fe fusion molecule, such as an scFv-Fc. fusion molecule comprising an scFv fragment and an Fc region from an antibody, related nucle ic acids, vectors, and host cells, and a method of inhibiting a viral infection in a mammal, which method comprises administering to a mammal in need thereo f the fusion molecule, wherein the fusion molecule binds to an epitope of a viral envelope protein that is inaccessible to whole immunoglobulin molecule s due to molecular steric hindrance, or a nucleic acid, optionally in the form of a vector, encoding same, wherein the nucleic acid or vector is optionally contained within a host cell.</p>
申请公布号 CA2553788(A1) 申请公布日期 2006.07.06
申请号 CA20042553788 申请日期 2004.09.29
申请人 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SE CRE 发明人 DIMITROV, DIMITER S.;ZHANG, MEI-YUN
分类号 A61K39/21;C07K16/08 主分类号 A61K39/21
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