摘要 |
<p>A. (poly)peptide-Fe fusion molecule, such as an scFv-Fc. fusion molecule comprising an scFv fragment and an Fc region from an antibody, related nucle ic acids, vectors, and host cells, and a method of inhibiting a viral infection in a mammal, which method comprises administering to a mammal in need thereo f the fusion molecule, wherein the fusion molecule binds to an epitope of a viral envelope protein that is inaccessible to whole immunoglobulin molecule s due to molecular steric hindrance, or a nucleic acid, optionally in the form of a vector, encoding same, wherein the nucleic acid or vector is optionally contained within a host cell.</p> |