发明名称 |
Mesylates of piperazine derivatives and process for their preparation |
摘要 |
The invention relates to the mesylates of a group of piperazine derivatives and to a process for the preparation of these mesylates in an economic way in the high yield and of high purity. According to the process of the invention the synthesis of the piperazine ring and the mesylate formation are combined in a single reaction step. The invention relates to the mesylate of compounds of the formula (I) wherein X is a bicyclic heterocyclic phenyl group and Y is methyl, ethyl (optionally substituted with fluorine), cycloalkyl (3-7C) methyl, benzyl or m-phenyl benzyl
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申请公布号 |
US7030241(B2) |
申请公布日期 |
2006.04.18 |
申请号 |
US20030468098 |
申请日期 |
2003.08.15 |
申请人 |
SOLVAY PHARMACEUTICALS B.V. |
发明人 |
VAN AAR MARCEL P. M.;SCHOUTEN STEFANUS J.;ZORGDRAGER JAN;HESLINGA MICHIEL C. |
分类号 |
C07D403/00;C07D263/58;C07D401/00;C07D405/00;C07D409/00 |
主分类号 |
C07D403/00 |
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