发明名称 PYRROLE-2, 5-DITHIONE DERIVATIVES AS LIVER X RECEPTOR MODULATORS.
摘要 <p>The present invention relates to certain novel compounds of the Formula I to processes for preparing such compounds, to their the utility in modulation of nuclear hormone receptors Liver X Receptor (LXR) alpha (NR1H3) and/or beta (NR1H2) and in treating clinical conditions including cardiovascular diseases such as atherosclerosis; inflammatory diseases, Alzheimer s disease, lipid disorders (dyslipidemias) whether or not associated with insulin resistance, type 2 diabetes and other manifestations of the metabolic syndrome, to methods for their therapeutic use and to pharmaceutical compositions containing them.</p>
申请公布号 MXPA06000447(A) 申请公布日期 2006.04.07
申请号 MX2006PA00447 申请日期 2004.07.08
申请人 ASTRAZENECA AB 发明人 PATRIK HOLM
分类号 A61K31/4025;A61K31/4439;A61P3/10;A61P25/28;C07D207/36;C07D207/44;C07D401/06;C07D403/06;(IPC1-7):A61K31/402;A61K31/443 主分类号 A61K31/4025
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