RAPID PROGNOSTIC ASSAY FOR MALIGNANCIES TREATED WITH EPIDERMAL GROWTH FACTOR RECEPTOR
摘要
<p>A molecular assay for determining the sensitivity or resistance of malignancies to chemotherapy prior to initiation of chemotherapy and which also allows for monitoring the therapeutic effects of the chemotherapy during treatment. The molecular assay measures tumor response to therapy with EGFR modulators and utilizes tumor mRNA as a starting material and a quantitative measurement of c-fos expression as an analytical endpoint.</p>
申请公布号
WO2006026710(A2)
申请公布日期
2006.03.09
申请号
WO2005US31121
申请日期
2005.08.31
申请人
THE JOHNS HOPKINS UNIVERSITY;KULESZA, PIOTR;JIMENO, ANTONIO;HIDALGO, MANUEL, MEDINA;CLARK, DOUGLAS, PAUL;KINCAID, ERIK, ALLAN
发明人
KULESZA, PIOTR;JIMENO, ANTONIO;HIDALGO, MANUEL, MEDINA;CLARK, DOUGLAS, PAUL;KINCAID, ERIK, ALLAN