发明名称 |
Compositions and methods for determining and predicting treatment responses for depression and anxiety |
摘要 |
The invention provides genetic means, including compositions (e.g., kits) and methods, to predict the efficacy of a treatment in depression and anxiety and to predict a patient's response to a particular a specific medication or treatment. The invention provides methods for diagnosing the presence of a psychiatric disorder or determining the outcome of a treatment for a psychiatric disorder. The invention provides methods for methods for diagnosing the presence of a psychiatric disorder in an individual by determining what corticotropin-releasing hormone receptor 1 (CRHR1) protein or transcript isoforms are expressed in an individual. The invention provides methods for diagnosing the presence of a psychiatric disorder in an individual by determining what protein or transcript isoforms are expressed in an individual wherein the protein is involved in the hypothalamic-pituitary-adrenal (HPA) axis pathway. |
申请公布号 |
AU2005271244(A1) |
申请公布日期 |
2006.02.16 |
申请号 |
AU20050271244 |
申请日期 |
2005.08.12 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
KATHERINE MISOURAS IRIZARRY;KRISTOPHER J. L. IRIZARRY;JULIO LICINIO;MA-LI WONG |
分类号 |
A61K38/17;A61K31/495 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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