发明名称 Heterocyclic tripeptides as hepatitis C inhibitors
摘要 A compound of formula (I) wherein R1 is hydroxy or NHSO2R1A wherein R1A is (C1-8)alkyl, (C3-7)cycloalkyl or {(C1-6)alkyl-(C3-7)cycloalkyl}, which are all optionally substituted from 1 to 3 times with halo, cyano, nitro, O-(C1-6)alkyl, amido, amino or phenyl, or R1A is C6 or C10 aryl which is optionally substituted from 1 to 3 times with halo, cyano, nitro, (C1-6)alkyl, O-(C1-6)alkyl, amido, amino or phenyl; R2 is t-butyl, -CH2-C(CH3)3, or -CH2-cyclopentyl; R3 is t-butyl or cyclohexyl and R4 is cyclobutyl, cyclopentyl, or cyclohexyl; or a pharmaceutically acceptable salt thereof.
申请公布号 NZ534730(A) 申请公布日期 2005.12.23
申请号 NZ20030534730 申请日期 2003.01.24
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH 发明人 LLINAS-BRUNET, MONTSE;BAILEY, MURRAY DOUGLAS;GHIRO, ELISE
分类号 C12N15/09;A61K31/7056;A61K38/00;A61K38/21;A61P1/16;A61P31/00;A61P31/14;C07D417/14;C07K5/08;C07K5/083;C07K5/087;(IPC1-7):C07D417/14;C07K4/00;A61K31/47 主分类号 C12N15/09
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