| 摘要 |
PROBLEM TO BE SOLVED: To obtain a disinfectant having improved properties in any one of points such as (1) bactericidal action at a low concentration, (2) rapid bactericidal action in a short time, (3) bactericidal action having persistence, (4) low toxicity, and (5) stability without lowering the effect even when an organic substance is mixed, and an antibacterial compound of a new type against Gram-positive bacteria and Eumycetes in answer to the problem of appearance of a resistant bacterium, or the like. SOLUTION: A novel photodecomposition product (ANDP-8) of acrinol obtained by separating the main component in the photodecomposition product (ANDP) of acrinol and purifying it has an activity against Gram-positive bacteria of about 10-100 times the activity of acrinol as its original substance, and has also considerably strong antibacterial action against Eumycetes against which no antibacterial power is recognized with acrinol. The acridine derivative is represented by formula (I) or its pharmaceutically acceptable salt. COPYRIGHT: (C)2006,JPO&NCIPI
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