发明名称 |
SULPHUR-LINKED IMIDAZOLE COMPOUNDS FOR THE TREAMENT OF HIV |
摘要 |
This invention relates to isophthalonitrile derivatives of formula (I) or pharmaceutically acceptable salts, solvates or derivative thereof, wherein R 1 to R3 are defined in the description, and to processes for the preparation thereof, intermediates used in their preparation of, compositions containing them and the uses of such derivatives.The compounds of the present invention bind to the enzyme reverse transcriptase and are modulators, especially inhibitors thereof.
|
申请公布号 |
CA2562846(A1) |
申请公布日期 |
2005.10.27 |
申请号 |
CA20052562846 |
申请日期 |
2005.04.11 |
申请人 |
PFIZER LIMITED |
发明人 |
JONES, LYN HOWARD;MOHAMMED, SHAHID;SELBY, MATTHEW DUNCAN;SWAIN, NIGEL ALAN;STUPPLE, PAUL ANTHONY;MOWBRAY, CHARLES ERIC;NEWMAN, SANDRA DORA |
分类号 |
C07D233/84;A61K31/4164;A61K31/4439;A61P31/18;C07D401/12 |
主分类号 |
C07D233/84 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|