发明名称 VACCINE IMMUNOTHERAPY FOR IMMUNE SUPPRESSED PATIENTS
摘要 A method for overcoming mild to moderate immune suppression includes the steps of inducing production of naive T-cells and restoring T-cell immunity. A method of vaccine immunotherapy includes the steps of inducing production of naive T-cells and exposing the naive T-cells to endogenous or exogenous antigens at an appropriate site. Additionally, a method for unblocking immunization at a regional lymph node includes the steps of promoting differentiation and maturation of immature dendritic cells at a regional lymph node and allowing presentation of processed peptides by resulting mature dendritic cells, thus, for example, exposing tumor peptides to T-cells to gain immunization of the T-cells. Further, a method of treating cancer and other persistent lesions includes the steps of administering an effective amount of a natural cytokine mixture as an adjuvant to endogenous or exogenous administered antigen to the cancer or other persistent lesions.
申请公布号 EP1337149(A4) 申请公布日期 2005.10.12
申请号 EP20010988547 申请日期 2001.10.26
申请人 IRX THERAPEUTICS, INC. 发明人 HADDEN, JOHN, W.
分类号 A61K45/00;A61K31/192;A61K31/365;A61K31/405;A61K31/415;A61K31/664;A61K38/00;A61K38/19;A61K39/00;A61K39/39;A61P31/00;A61P35/00;C12N15/19;C12P21/08 主分类号 A61K45/00
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