发明名称 METHOD FOR PRODUCING 4-NITROIMIDAZOLE COMPOUND
摘要 The present invention provides a method for producing a 4-nitroimidazole compound represented by general formula (1) at high yield and at high purity by a safe method causing few dangers such as explosion. The production metho d of the present invention comprises iodinating a 4-nitroimidazole compound represented by general formula (2): wherein each of X1 and X2 represents a chlorine atom or bromine atom, and then reducing the obtained 5-iodo-4- nitroimidazole compound represented by general formula (3): wherein X2 is th e same as defined above.
申请公布号 CA2555372(A1) 申请公布日期 2005.08.25
申请号 CA20052555372 申请日期 2005.02.15
申请人 OTSUKA PHARMACEUTICAL CO., LTD. 发明人 SHINHAMA, KOICHI
分类号 C07D233/92 主分类号 C07D233/92
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