PRODRUG COMPRISING 5-AMINOSALICYLATE GLYCOSIDE

摘要

It is intended to provide a remedy for ulcerative colitis by which 5- aminosalicylic acid (5-ASA) useful as a remedy for ulcerative colitis can be efficiently delivered to the affected site (i.e., the large intestine) with little absorption or metabolism in the stomach or the upper part of the smal l intestine and which is highly safe and can be administered over a long time. Namely, 5-ASA carrying D-galactose introduced thereinto which is represented by the following general formula [1]. [1] This compound can efficiently get to the function site (i.e., the large intestine). Then the intestinal flora decomposes it to thereby form 5-ASA which is the active ingredient in the large intestine.