发明名称 BASIC DERIVATIVES OF GLUTAMIC ACID AND ASPARTIC ACID AS GASTRIN OR CHOLECYSTOKININ ANTAGONISTS
摘要 Compounds of general formula (I), in which r is 1 or 2, R1 is selected independently from: unsubstituted, mono- or di-substituted phenyl groups, unsubstituted, mono- or di-substituted phenylamino groups, the 2(beta)-naphthyl group, and heterocyclic, monocyclic or dicyclic groups; R2 is selected independently from: heterocyclic spiro groups, aminoalkyladamantyl groups, alkylamino groups, C4-C10 cycloalkylamino groups , and dicyclic amino groups (condensed); R3 is H, CH3 or C2H5; A is a bond or a linear or branched alkylene group comprising from 1 t o 4 carbon atoms; W is a tertiary amino group or a heterocyclic group.
申请公布号 CA2132537(C) 申请公布日期 2005.08.02
申请号 CA19932132537 申请日期 1993.04.06
申请人 ROTTA RESEARCH LABORATORIUM S.P.A. 发明人 ROVATI, ANGELO L.;MAKOVEC, FRANCESCO;ROVATI, LUCIO C.
分类号 C07D295/12;A61K31/40;A61K31/435;A61K31/4427;A61K31/443;A61K31/445;A61K31/47;A61K31/472;A61K31/495;A61K31/535;A61K31/5375;A61P1/00;A61P1/04;A61P1/16;A61P1/18;A61P13/02;A61P13/06;A61P15/00;A61P25/00;A61P25/22;A61P27/02;A61P27/12;A61P43/00;C07C237/22;C07D207/09;C07D207/14;C07D215/54;C07D217/06;C07D221/20;C07D295/13;C07D295/18;C07D295/185;C07D401/12;C07D405/12;C07D453/02;(IPC1-7):C07D295/13;C07D207/06;C07D403/12;C07D413/12;C07D413/14;A61K31/165;C07D211/26;A61K31/395 主分类号 C07D295/12
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