THIAZOLINE DERIVATIVE AND APPLICATION OF THE SAME

摘要

PROBLEM TO BE SOLVED: To obtain a thiazoline derivative useful as a therapeutic agent for thrombosis. SOLUTION: The thiazoline derivative is a compound expressed by formula (I) or its salt. In the formula, R expresses a cyclic hydrocarbon group which may be substituted or a heterocyclic group which may be substituted; X expresses a bond or a divalent chain hydrocarbon group which may be substituted; X' expresses a bond or an N(R5); Y expresses a divalent hydrocarbon group which may be substituted; Y' expresses a bond or C(=O); the ring A expresses an N-containing heterocyclic ring which may be substituted; Z1and Z3independently express a bond or a divalent chain hydrocarbon group which may be substituted; Z2expresses a bond or an N(R6); B expresses a group expressed by formula (II). COPYRIGHT: (C)2005,JPO&NCIPI