发明名称 |
HEPATOCELLULAR CARCINOMA SPECIFIC PROMOTER AND USES THEREOF |
摘要 |
<p>Liver cancer, particularly hepatocellular carcinoma specific promoter sequences and adenovirus vehicles are provided. By providing for transcriptional initiating regulation dependent upon transcription factors that are only active in specific, limited cell types, virus replication will be restricted to the target cells. The modified adenovirus may be used as a vehicle for introducing new genetic capability, particularly associated with cytotoxicity, for treating neoplasia.</p> |
申请公布号 |
WO2005040188(A1) |
申请公布日期 |
2005.05.06 |
申请号 |
WO2004US31477 |
申请日期 |
2004.09.24 |
申请人 |
CELL GENESYS, INC.;ARROYO, TRINI;LI, YUANHAO |
发明人 |
ARROYO, TRINI;LI, YUANHAO |
分类号 |
A61K35/76;A61K48/00;C07H21/04;C12N5/08;C12N7/00;C12N15/861;(IPC1-7):C07H21/04 |
主分类号 |
A61K35/76 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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