Novel metastasis suppressor gene on human chromosome 8

摘要

An isolated or purified nucleic acid molecule encoding the metastasis suppressor gene, Tey 1, located at p21-p12 on human chromosome 8. The invention further includes methods of treating cancer comprising administering a nucleic acid molecule encoding Tey 1 or administering an isolated Tey 1 polypeptide. The invention further includes methods of diagnosing or prognosticating cancer in a mammal comprising assaying for the level of Tey 1.