| 发明名称 |
DERIVES HYDROXY SUBSTITUE DE 2-ALKYLIDENE HYDROXYCUMARANONES A ACTIVITE uPA-uPAR ANTAGONISTE COMME AGENT ANTITUMORAL ET/OU ANTIMETASTATIQUE. |
| 摘要 |
Compounds of the formulawherein R,R', A,B,T and x have the meaning given in the specification possess uPA (urokinase-type plasminogen activator) antagonist activity and can be employed as antitumor and/or antimetastatic agents. |
| 申请公布号 |
MA26528(A1) |
申请公布日期 |
2004.12.20 |
| 申请号 |
MA19980025200 |
申请日期 |
1998.07.31 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG. |
发明人 |
GIANPIERO DE CILLIS;BERNHARD KONIG;ROBERTO DI DOMENICO;AMBROGIO OLIVA |
| 分类号 |
A61K31/343;A61K31/37;A61K31/443;A61K31/4433;A61K31/445;A61K31/4525;A61K31/495;A61K31/496;A61P35/00;C07D307/79;C07D307/83;C07D405/12;C07D405/14;C07D409/14 |
主分类号 |
A61K31/343 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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