发明名称 KATIONISCHE KOPOLYMERE VON VINYLAMINE UND VINYLALKOHOL ZUR VERABREICHUNG VON OLIGONUKLEOTIDEN
摘要 The present invention relates to an improved method for the cytoplasmic delivery of oligonucleotides using cationic copolymers based on vinyl alcohol with low levels of vinyl amine (PVAVAMs). Improved compositions for use in such method are also provided.
申请公布号 AT282433(T) 申请公布日期 2004.12.15
申请号 AT19960902128T 申请日期 1996.01.11
申请人 AMGEN INC. 发明人 GOLDENBERG, MERRILL, S.;BEEKMAN, ALICE, C.
分类号 A61K31/70;A61K47/48;A61K48/00;C12N15/113;C12N15/88;(IPC1-7):A61K48/00 主分类号 A61K31/70
代理机构 代理人
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