发明名称 |
DETECTING DNA SEQUENCE VARIATIONS |
摘要 |
A method of analysing a polynucleotide target involves incubating the target with an oligonucleotide probe, generally an array of immobilised oligonucleotide probes, to form a duplex, and using ligase or polymerase to extend one chain of the duplex. A point mutation or variable number tandem repeat section may be analysed. Arrays of immobilised oligonucleotides are provided for use in the method. |
申请公布号 |
EP0820524(B1) |
申请公布日期 |
2004.12.01 |
申请号 |
EP19960909255 |
申请日期 |
1996.04.09 |
申请人 |
OXFORD GENE TECHNOLOGY IP LIMITED |
发明人 |
SOUTHERN, EDWIN, MELLOR;PRITCHARD, CLARE, ELIZABETH;CASE-GREEN, STEPHEN, CHARLES |
分类号 |
C12P19/34;C12Q1/68;G01N33/53;G01N37/00 |
主分类号 |
C12P19/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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