| 摘要 |
The present invention relates to a method of characterising a nucleic acid region and, more particularly, to a method of analysing a marker nucleic aci d region. The method of the present invention is based on identification of on e or both of the nucleic acid regions flanking a marker nucleic acid region an d provides a means of analysing a marker nucleic acid region which is characteristic of a clonal population of cells. The method of the present invention is useful in the context of enabling a range of applications including, but not limited to, monitoring the progression of a condition characterised by the presence of a clonal populations of cells (such as a neoplastic condition), monitoring the levels of one or more clonal cell population, predicting the likelihood of a subject's relapse from a remissiv e state to a disease state, for assessing the effectiveness of existing therapeutic drugs and/or new therapeutic agents and identifying the presence of a marker region.
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