PREPARATION OF METAL MESOPORPHYRIN HALIDE COMPOUNDS
摘要
A method of preparing metal mesoporphyrin halide compounds is described. The metal mesoporphyrin halide compound may be formed by forming a novel mesoporphyrin IX intermediate compound and then converting the mesoporphyrin IX intermediate to the metal mesoporphyrin halide through metal insertion. The novel intermediate compound may be formed by a catalytic hydrogenation of hemin in acid and subsequent recovery.
申请公布号
WO03101999(A3)
申请公布日期
2004.09.10
申请号
WO2003US17426
申请日期
2003.06.03
申请人
WELLSPRING PHARMACEUTICAL CORPORATION
发明人
VUKOVICH, ROBERT;LEVINSON, BENJAMIN;CAROSELLI, ROBERT;DRUMMOND, GEORGE;ANTCZAK, KAZIMIERZ;BOUCHER, CHRISTOPHER;MORTIMER, RICHARD