发明名称 |
Spirocyclic ligands for sigma receptors, and libraries and methods of use thereof |
摘要 |
One aspect of the present invention relates to spirocyclic compounds. Another aspect of the present invention relates to the use of the spirocyclic compounds as ligands for mammalian G-protein-coupled receptors or sigma receptors. The present invention also relates to methods of modulating the activity of a G-protein-coupled receptor or a sigma receptor in a mammal using the spirocyclic compounds of the present invention. The present invention also relates to methods of treating various diseases in a mammal using the spirocyclic compounds of the present invention.
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申请公布号 |
US6762177(B2) |
申请公布日期 |
2004.07.13 |
申请号 |
US20020289119 |
申请日期 |
2002.11.05 |
申请人 |
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发明人 |
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分类号 |
A61P25/00;C07B61/00;C07D471/10;(IPC1-7):C07D471/10;C07D221/00;C07D223/00;A61K31/438;A61K31/55 |
主分类号 |
A61P25/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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