发明名称 |
Stable pharmaceutical solution formulations for pressurised metered dose inhalers |
摘要 |
An aerosol solution composition for use in an aerosol inhaler comprises an active material, a propellant containing a hydrofluoroalkane, a cosolvent and optionally a low volatility component to increase the mass median aerodynamic diameter (MMAD) of the aerosol particles on actuation of the inhaler. The composition is stabilized by using a small amount of mineral acid and a suitable can having part or all of its internal metallic surfaces made of stainless steel, anodized aluminium or lined with an inert organic coating. |
申请公布号 |
AU2000250701(B2) |
申请公布日期 |
2004.07.01 |
申请号 |
AU20000250701 |
申请日期 |
2000.05.22 |
申请人 |
CHIESI FARMACEUTICI S.P.A |
发明人 |
ALESSANDRA FERRARIS;GAETANO BRAMBILLA;BRIAN MEAKIN;DAVID GANDERTON;DAVID LEWIS |
分类号 |
A61K47/10;A61K;A61K9/00;A61K9/12;A61K9/72;A61K31/205;A61K31/46;A61K31/4704;A61K31/56;A61K31/57;A61K31/573;A61K47/04;A61K47/06;A61K47/14;A61L9/04;A61M15/00;B65D83/14;(IPC1-7):A61K009/12;B65D083/14 |
主分类号 |
A61K47/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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