发明名称 NEW SOLID COMPOUND OF 9- DEOXO-9A-AZA-9A-METHYL-9A- HOMOERYTHROMYCIN A AND METHOD FOR ITS PREPARATION.
摘要 Provided herein is a new compound [2R-(2R*, 3S*, 4R*, 5R*, 8R*, 10R*, 11R*, 12S*, 13S*, 14R*)]-13-[(2, 6-Dideoxy-3-C-methy-3-O-methyl-a-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4, 10- trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4, 6-trideoxy-3-(dimethylamino)-°-D-xyl-hexopiranosil] oxy]-1-oxa-6-azacyclopentadecan-15-one or with name of IUPAC 9- deoxo-9a-aza-9a-methyl-9a- homoerythromycin A and which is elucidated, for diverse physicochemical methods, which correspond with the and anhydrous and crystaline form with a tetragonal crystaline system, with spatial group P42212, cell constants a= 14.452 A0, b = 14.452 A0, c = 41.645 A0 and volume 8698 A03. Moreover, herein is depicted the process for obtaining it starting from the amine 9-deoxo-9a-aza-9a- homoerythromycin also denominated 11-aza-10-deoxo-10 dihydroerythromycin or known by the names azaerythromycin or amine azithromycin.
申请公布号 MXPA03004284(A) 申请公布日期 2004.05.19
申请号 MX2003PA04284 申请日期 2003.05.15
申请人 JOSE MANUEL FRANCISCO LARA OCHOA. 发明人 JOSE MANUEL FRANCISCO LARA OCHOA.
分类号 A61K31/7048;(IPC1-7):A61K31/704 主分类号 A61K31/7048
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