METHODS TO PREDICT EDEMA AS A SIDE EFFECT OF DRUG TREATMENT

摘要

This invention provides methods to predict the likelihood of occurrence of t he side effect of edema in patients treated with a drug including, but not limited to, a TKI, such as Imatinib or GLEEVEC.TM./GLIVEC.RTM.. The methods employed use gene expression profile comparisons and the determination of specific SNPs and in the IL-1.beta. gene. Methods of treatment of edema and kits for the performance of the above assays are also provided.