摘要 |
FIELD: organic synthesis. SUBSTANCE: invention provides novel benzamides with general formula I: (I), where R1 denotes group COOR4, in which R4 is non-branched or branched C1-C6-alkyl, or group CONR5R6, in which R5 and R6 are C1-C6-alkyls or, together with nitrogen atom, to which they are attached, form pyrrolidine, piperidine, hexamethylenimine, or morpholine; R2 represents chlorine, fluorine, trifluoromethyl, C1-C3-alkyl, or hydrogen; R3 hydroxy, C1-C6-alkyl, C1-C6-alkoxyl, or group CH2-NR5R6, in which R5 and R6 are as defined above. Compounds I manifest immunomodulating activity. EFFECT: extended choice of immunomodulators. 2 cl, 2 tbl, 6 ex |