发明名称 SUBSTITUTED BENZAMIDES
摘要 FIELD: organic synthesis. SUBSTANCE: invention provides novel benzamides with general formula I: (I), where R1 denotes group COOR4, in which R4 is non-branched or branched C1-C6-alkyl, or group CONR5R6, in which R5 and R6 are C1-C6-alkyls or, together with nitrogen atom, to which they are attached, form pyrrolidine, piperidine, hexamethylenimine, or morpholine; R2 represents chlorine, fluorine, trifluoromethyl, C1-C3-alkyl, or hydrogen; R3 hydroxy, C1-C6-alkyl, C1-C6-alkoxyl, or group CH2-NR5R6, in which R5 and R6 are as defined above. Compounds I manifest immunomodulating activity. EFFECT: extended choice of immunomodulators. 2 cl, 2 tbl, 6 ex
申请公布号 RU2221783(C2) 申请公布日期 2004.01.20
申请号 RU19990120663 申请日期 1999.09.23
申请人 发明人 GERMANN TINO;FROSH SHTEFANI;TSIMMER OSVAL'D
分类号 C07D211/42;A61K31/4412;A61K31/4468;A61K31/4545;A61P37/00;A61P37/02;C07D211/88;C07D211/94 主分类号 C07D211/42
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