发明名称 7-ARYL-3,9-DIAZABICYCLO(3.3.1)NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES
摘要 The invention relates to novel 3,9-diazabicyclo[3.3.1]nonene derivatives of formula (I) and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors or renin.
申请公布号 CA2483241(A1) 申请公布日期 2003.11.13
申请号 CA20032483241 申请日期 2003.04.08
申请人 ACTELION PHARMACEUTICALS LTD 发明人 FISCHLI, WALTER;REMEN, LUBOS;WELLER, THOMAS;WEBER, HANS-PETER;RICHARD-BILDSTEIN, SYLVIA;BUR, DANIEL;BEZENCON, OLIVIER
分类号 C07D471/08;A61K31/4995;A61K45/06;A61P3/10;A61P9/10;A61P9/12;A61P13/12;A61P15/10;A61P27/06;A61P37/02;C07D;(IPC1-7):C07D471/08;A61K31/499 主分类号 C07D471/08
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