发明名称 |
Crystal of bicalutamide and production method thereof |
摘要 |
The present invention relates to a crystal of bicalutamide having a defined form, as well as economical and industrially practical production methods of bicalutamide and a crystal thereof, which are superior in environmental benignity and safety. Accordingly, the present invention provides a production method of bicalutamide represented by the formula (I): which includes at least a step of reacting a compound represented by the formula (3): with an oxidizing agent, a production method of a crystal of bicalutamide, as well as a crystal form of bicalutamide as defined by X-ray diffraction (XRD) or solid <13>C NMR measurement.
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申请公布号 |
US2003191337(A1) |
申请公布日期 |
2003.10.09 |
申请号 |
US20030362410 |
申请日期 |
2003.02.24 |
申请人 |
SHINTAKU TETSUYA;KATSURA TADASHI;ITAYA NOBUSHIGE |
发明人 |
SHINTAKU TETSUYA;KATSURA TADASHI;ITAYA NOBUSHIGE |
分类号 |
A61K;A61P;A61P5/28;A61P43/00;C07C;C07C315/02;C07C315/06;C07C317/26;C07C317/46;(IPC1-7):C07C317/34 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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