SALIVA-BASED METHODS FOR PREVENTING AND ASSESSING THE RISK OF DISEASES

摘要

This present invention provides compositions and methods for assessing the risk of a disease using salivary analysis. Specifically, the present invention provides a method for predicting the risk of a disease, comprising the steps of: a) providing a saliva sample from a subject; b) isolating a mucin in the saliva sample to produce an isolated mucin; and c) quantitating the content of a component in the isolated mucin, to predict the risk of a disease in the subject. The present invention also provides methods for reducing the risk of a disease and diagnostic kits for detecting a disease based on measurement of the content of a component in a salivary mucin.