发明名称 Biodegradable/bioactive nucleus pulposus implant and method for treating degenerated intervertebral discs
摘要 A bioactive/biodegradable nucleus implant for repairing degenerated intervertebral discs that is inflated inside the nucleus space after the degenerated nucleus has been removed to re-pressurize the nuclear space within the intervertebral disc. The implant is inflated with a high molecular weight fluid, gel or combination of fluid and elastomer, preferably an under-hydrated HA hydrogel/growth factor mixture with or without host cells. The implant includes an internal, integral, self-sealing valve that allows one-way filling of the implant after it is placed within the disc, and is made from a material that allows fibrous in growth thereby stabilizing the implant. A variety of substances can be incorporated into the implant to promote healing, prevent infection, or arrest pain.
申请公布号 US2003033017(A1) 申请公布日期 2003.02.13
申请号 US20020154857 申请日期 2002.05.24
申请人 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 发明人 LOTZ JEFFREY C.;COLLIOU OLIVIER K.;BRADFORD DAVID S.
分类号 A61F2/00;A61F2/02;A61F2/30;A61F2/44;A61F2/46;A61L27/18;A61L27/58;B29C41/14;B29C41/42;(IPC1-7):A61F2/44 主分类号 A61F2/00
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