发明名称 Auto micro emulsifiable pharmaceutical compositions useful for prevention of cardiovascular disorders, especially atheroma, contains statins that are more effectively absorbed on oral administration
摘要 Auto micro emulsifiable pharmaceutical compositions for oral administration. Auto micro emulsifiable pharmaceutical compositions for oral administration contains: (a) an active component that is seriously affected by the initial intestinal passage; (b) a lipophilic phase that comprises a mixture of glycerol mono-, di-, and triesters and PEG mono- and diesters, together with a 8 - 18C fatty acid; (c) a surfactant (TA) phase that is a mixture of glycerol mono-, di-, and triesters and PEG mono- and diesters with caprylic and capric acids; (d) a cosurfactant (CoTA) phase comprising at least one ester of an alcohol and a fatty acid that is a propylene glycol caprylic ester, propylene glycol lauric ester, and/or polyglycerol oleic ester. The ratio of TA/CoTA being 0.2 - 6.
申请公布号 FR2827770(A1) 申请公布日期 2003.01.31
申请号 FR20010010094 申请日期 2001.07.27
申请人 GATTEFOSSE S.A. 发明人 BENAMEUR HASSAN;JANNIN VINCENT;ROULOT DELPHINE
分类号 A61K47/14;A61K9/107;A61K9/48;A61K31/366;A61K47/44;A61P3/06;A61P9/10;(IPC1-7):A61K9/107 主分类号 A61K47/14
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