发明名称 |
ATOPY |
摘要 |
The present invention relates to isolated nucleic acid sequences of ANGE, CLLD8 and CLLD7 or sequences complementary or substantially homologous thereto or fragments thereof. Also provided are sequences comprising hybrid nucleic acid sequences from two or more of the genes. Also provided are nucleic acid expression vectors, polypeptides, antibodies to the polypeptides, host cells, non-human transgenic animals and pharmaceutical compositions and agents. Also provided is the use of the nucleic acid sequence and/or protein in medicine and research, methods for diagnosing or determining predisposition to disease or severity of disease, methods for preventing or treating disease, and kits for use in the methods and the use of the nucleic acid sequence and protein in treating or preventing IgE mediated diseases and non-atopic asthma, and in screens for identifying new agents for use in the methods. |
申请公布号 |
WO03000727(A2) |
申请公布日期 |
2003.01.03 |
申请号 |
WO2002GB02859 |
申请日期 |
2002.06.21 |
申请人 |
ISIS INNOVATIONS LIMITED;ZHANG, YOUMING;MOFFATT, MIRIAM;COOKSON, WILLIAM;TINSLEY, JON |
发明人 |
ZHANG, YOUMING;MOFFATT, MIRIAM;COOKSON, WILLIAM;TINSLEY, JON |
分类号 |
A01K67/027;A61K31/7088;A61K38/00;A61K39/395;A61K45/00;A61K48/00;A61P11/02;A61P11/06;A61P17/00;A61P17/02;A61P37/02;A61P37/08;C07K14/47;C07K16/18;C12M1/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/12;C12P21/02;C12Q1/02;C12Q1/68;G01N33/15;G01N33/50 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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