摘要 |
PROBLEM TO BE SOLVED: To provide a medicinal amide compound capable of selectively controlling the production of IL-4 which especially deeply participates in the condition formation and advance of allergic diseases, in cytokine produced from Th 2 cells. SOLUTION: This amide compound represented by general formula (I) [R<1> is a halogen, an alkyl, an alkoxy, or the like; the ring Q is benzene, a heterogeneous aromatic ring, or the like which may have one or more substituents; R<2> is H, an alkyl, or the like; Z is CH or N; R<3> is a halogen, cyano, nitro, or amino; R<5> is an alkyl, N (R<6> ) (R<7> ) (R<6> and R<7> are the same as or different from each other and each H, an alkyl or the like, or R<6> and R<7> form a cyclic amine together with the adjacent nitrogen atom, or the like), or the like] or its medicinally acceptable salt.
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