发明名称 AMIDE COMPOUND AND ITS MEDICINAL USE
摘要 PROBLEM TO BE SOLVED: To provide a medicinal amide compound capable of selectively controlling the production of IL-4 which especially deeply participates in the condition formation and advance of allergic diseases, in cytokine produced from Th 2 cells. SOLUTION: This amide compound represented by general formula (I) [R<1> is a halogen, an alkyl, an alkoxy, or the like; the ring Q is benzene, a heterogeneous aromatic ring, or the like which may have one or more substituents; R<2> is H, an alkyl, or the like; Z is CH or N; R<3> is a halogen, cyano, nitro, or amino; R<5> is an alkyl, N (R<6> ) (R<7> ) (R<6> and R<7> are the same as or different from each other and each H, an alkyl or the like, or R<6> and R<7> form a cyclic amine together with the adjacent nitrogen atom, or the like), or the like] or its medicinally acceptable salt.
申请公布号 JP2002338537(A) 申请公布日期 2002.11.27
申请号 JP20010146915 申请日期 2001.05.16
申请人 MITSUBISHI PHARMA CORP 发明人 NAITO YOICHIRO;USHIO HIROYUKI;HOSHINO YUKIO;KAGOSHIMA MASAHIKO;OSHITA KOICHI;KATAOKA HIROTOSHI;CHIBA KENJI
分类号 C07D307/68;A61K31/277;A61K31/341;A61K31/438;A61K31/4427;A61K31/443;A61K31/4433;A61K31/451;A61K31/4525;A61K31/4535;A61K31/454;A61K31/4545;A61K45/06;A61P11/02;A61P11/06;A61P17/00;A61P37/08;A61P43/00;C07C255/60;C07D211/46;C07D401/12;C07D405/12;C07D405/14;C07D407/12;C07D409/12;C07D413/12;C07D417/12;C07D491/113;(IPC1-7):C07C255/60;A61K31/452;A61K31/453 主分类号 C07D307/68
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