TOPICAL COMPOSITIONS CONTAINING NONIMMUNOSUPPRESSIVE CYCLOSPORIN_DERIVATIVES FOR TREATING HAIR LOSS

摘要

The present invention discloses a topical scalp and transdermal preparation with excellent penetration to the skin and follicle, containing a [ gamma -hydroxy-N-methyl-L-leucine<4>] cylosporin derivative which is a non-immunosuppressive component with hair growth stimulating ability. The topical scalp and transdermal preparation is prepared by incorporating the cyclosporin derivative into a liposome, microcapsule, micro-sphere, composite particle or emulsion, capable of being employed as a hair growth stimulating agent and applied for the prevention of hair loss.