METHODS OF SCREENING FOR COMPOUNDS THAT MODULATE HORMONE RECEPTOR ACTIVITY

摘要

The present invention provides methods for identifying an effective agent th at modulates a biological activity of a nuclear hormone receptor. In a method o f the invention, an isolated receptor-containing complex is assayed for an altered modification state as compared to a control modification state. The presence of an altered modification state serves to identify an effective agent that modulates a biological activity of the nuclear hormone receptor.< /SDOAB>