摘要 |
<p>A pH-dependent sustained release, drug delivery composition capable of being formed into tablets or pellets, wherein the release is controlled by a diffusion barrier formed by the interaction of a pH-dependent gelling material and a pH-independent non-gelling material, comprising a polymer matrix comprising, by weight, (a) 10 to 50 % sodium alginate, (b) 2 to 15 % propylene glycol alginate and (c) 40 to 80 % of a pharmaceutical medicament.</p> |