发明名称 MIXED STRUCTURES RESULTING FROM THE INCORPORATION OF A BIOLOGICAL MACROMOLECULE, ESPECIALLY DNA, IN A LIQUID CRYSTAL PHASE OF AMPHIPHILES, AND VESICLES OBTAINED USING THESE STRUCTURES
摘要 The invention relates to a structured mixed phase formed by the incorporation of a biological macromolecule into a liquid-crystal phase of amphiphiles, preferably a lamellar phase, wherein said biological macromolecule is present in said structured mixed phase in an amount of at least 5% by weight, based on the amphiphilic compounds constituting said liquid-crystal phase of amphiphiles, and wherein at least one of the two entities consisting of the biological macromolecules, on the one hand, and all the amphiphilic compounds, on the other, is of an uncharged nature. The biological macromolecules incorporated into the structured mixed phases of the invention are preferably selected from polynucleotides, particularly DNA or RNA, proteins and polysaccharides. The invention further relates to vesicles obtained by dispersion of the above structured mixed phases.
申请公布号 EP1239834(A2) 申请公布日期 2002.09.18
申请号 EP20000990090 申请日期 2000.12.21
申请人 CAPSULIS 发明人 POTT, TANJA;LAVERSANNE, RENE;ROUX, DIDIER
分类号 A61K9/127;A61K48/00;(IPC1-7):A61K9/127;A61K9/133 主分类号 A61K9/127
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