发明名称 HYALINE CARTILAGE REPLACEMENT SUBSTANCE
摘要 Means for replacing hyaline cartilage that is capable of self-assembly in the absence of covalent cross-linking. Further, aggregates of the means are biphasic, containing both peptide and water. The means comprises one or more than one polypeptide having a sequence according to SEQ ID NO:1, SEQ ID NO:2 or SEQ ID NO:3, or comprises a sequence where one or more than one amino acid is conservatively substituted, or where one or more than one amino acid is substituted to promote cross-linking between individual polypeptides.
申请公布号 WO0241757(A3) 申请公布日期 2002.07.25
申请号 WO2001US43489 申请日期 2001.11.16
申请人 LOMA LINDA UNIVERSITY;SANDBERG, LAWRENCE, B.;JIMENEZ, FELIPE, JR. 发明人 SANDBERG, LAWRENCE, B.;JIMENEZ, FELIPE, JR.
分类号 A61L27/22;A61L27/36;C07K14/435 主分类号 A61L27/22
代理机构 代理人
主权项
地址