发明名称 |
HYALINE CARTILAGE REPLACEMENT SUBSTANCE |
摘要 |
Means for replacing hyaline cartilage that is capable of self-assembly in the absence of covalent cross-linking. Further, aggregates of the means are biphasic, containing both peptide and water. The means comprises one or more than one polypeptide having a sequence according to SEQ ID NO:1, SEQ ID NO:2 or SEQ ID NO:3, or comprises a sequence where one or more than one amino acid is conservatively substituted, or where one or more than one amino acid is substituted to promote cross-linking between individual polypeptides. |
申请公布号 |
WO0241757(A3) |
申请公布日期 |
2002.07.25 |
申请号 |
WO2001US43489 |
申请日期 |
2001.11.16 |
申请人 |
LOMA LINDA UNIVERSITY;SANDBERG, LAWRENCE, B.;JIMENEZ, FELIPE, JR. |
发明人 |
SANDBERG, LAWRENCE, B.;JIMENEZ, FELIPE, JR. |
分类号 |
A61L27/22;A61L27/36;C07K14/435 |
主分类号 |
A61L27/22 |
代理机构 |
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代理人 |
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地址 |
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